How successful is repeat testicular sperm extraction in patients with azoospermia?
Identifieur interne : 001648 ( Main/Exploration ); précédent : 001647; suivant : 001649How successful is repeat testicular sperm extraction in patients with azoospermia?
Auteurs : Vale Rie Vernaeve [Belgique, Espagne] ; G. Verheyen [Belgique] ; A. Goossens [Belgique] ; A. Van Steirteghem [Belgique] ; P. Devroey [Belgique] ; H. Tournaye [Belgique]Source :
- Human Reproduction [ 0268-1161 ] ; 2006-06.
English descriptors
- KwdEn :
Abstract
BACKGROUND: Little is known about the extraction rate in repeated sperm retrieval procedures in azoospermic patients. This study aimed to assess the feasibility of repeated sperm recovery in these patients. METHODS: A total of 1066 azoospermic men had their first sperm recovery between 1 January 1995 and 31 December 2003. A total of 381 men had obstructive azoospermia (OA), 628 nonobstructive azoospermia (NOA) and 57 showed hypospermatogenesis. RESULTS: Overall, sperm could be retrieved in all procedures in the 598 cycles performed in OA men (100%). A total of 117, 57, 24, 11, 7 and 1 men underwent, respectively, two, three, four, five, six and seven sperm retrievals; all were successful. Of the 784 procedures performed on the 628 men with NOA, sperm could be retrieved in 384 procedures (49%). During the first testicular sperm extraction (TESE) procedure, sperm could be extracted in 261 men with NOA (41.6%). A total of 103 men had a second attempt, 34 had a third attempt, 11 had a fourth attempt, 6 had a fifth attempt and 2 had a sixth attempt. In these cycles, sperm could be extracted in, respectively, 77 (74.7%), 28 (82.3%), 11 (100%), 5 (83.3%) and 2 (100%) men. CONCLUSION: Repeated TESE ensures a high sperm recovery rate even in patients with NOA. In NOA patients, studies reporting on TESE may therefore overestimate the retrieval rate by reallocating successful patients. These data also show that when no spermatozoa can be obtained after thawing cryopreserved testicular sperm for ICSI in NOA patients, a repeat TESE procedure can be planned.
Url:
DOI: 10.1093/humrep/del012
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream Istex, to step Corpus: 000494
- to stream Istex, to step Curation: 000494
- to stream Istex, to step Checkpoint: 001094
- to stream Main, to step Merge: 001656
- to stream Main, to step Curation: 001648
Le document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">How successful is repeat testicular sperm extraction in patients with azoospermia?</title><author><name sortKey="Vernaeve, Vale Rie" sort="Vernaeve, Vale Rie" uniqKey="Vernaeve V" first="Vale Rie" last="Vernaeve">Vale Rie Vernaeve</name></author><author><name sortKey="Verheyen, G" sort="Verheyen, G" uniqKey="Verheyen G" first="G." last="Verheyen">G. Verheyen</name></author><author><name sortKey="Goossens, A" sort="Goossens, A" uniqKey="Goossens A" first="A." last="Goossens">A. Goossens</name></author><author><name sortKey="Van Steirteghem, A" sort="Van Steirteghem, A" uniqKey="Van Steirteghem A" first="A." last="Van Steirteghem">A. Van Steirteghem</name></author><author><name sortKey="Devroey, P" sort="Devroey, P" uniqKey="Devroey P" first="P." last="Devroey">P. Devroey</name></author><author><name sortKey="Tournaye, H" sort="Tournaye, H" uniqKey="Tournaye H" first="H." last="Tournaye">H. Tournaye</name></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:96E1A1B9B1A984EA714030DA2F69002757219123</idno><date when="2006" year="2006">2006</date><idno type="doi">10.1093/humrep/del012</idno><idno type="url">https://api.istex.fr/document/96E1A1B9B1A984EA714030DA2F69002757219123/fulltext/pdf</idno><idno type="wicri:Area/Istex/Corpus">000494</idno><idno type="wicri:Area/Istex/Curation">000494</idno><idno type="wicri:Area/Istex/Checkpoint">001094</idno><idno type="wicri:doubleKey">0268-1161:2006:Vernaeve V:how:successful:is</idno><idno type="wicri:Area/Main/Merge">001656</idno><idno type="wicri:Area/Main/Curation">001648</idno><idno type="wicri:Area/Main/Exploration">001648</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">How successful is repeat testicular sperm extraction in patients with azoospermia?</title><author><name sortKey="Vernaeve, Vale Rie" sort="Vernaeve, Vale Rie" uniqKey="Vernaeve V" first="Vale Rie" last="Vernaeve">Vale Rie Vernaeve</name><affiliation wicri:level="3"><country xml:lang="fr">Belgique</country><wicri:regionArea>Clinica Eugin, Calle Entenza, Barcelona, Spain and Centre For Reproductive Medicine, University Hospital, Dutch-speaking Brussels Free University (Vrije Universiteit Brussel), Brussels</wicri:regionArea><placeName><settlement type="city">Bruxelles</settlement><region nuts="2">Région de Bruxelles-Capitale</region></placeName></affiliation><affiliation wicri:level="2"><country xml:lang="fr">Espagne</country><wicri:regionArea>3To whom correspondence should be addressed at: Clinica Eugin, Calle Entenza 293-295, 08029 Barcelona</wicri:regionArea><placeName><region nuts="2" type="communauté">Catalogne</region></placeName></affiliation><affiliation></affiliation></author><author><name sortKey="Verheyen, G" sort="Verheyen, G" uniqKey="Verheyen G" first="G." last="Verheyen">G. Verheyen</name><affiliation wicri:level="3"><country xml:lang="fr">Belgique</country><wicri:regionArea>Centre For Reproductive Medicine, University Hospital, Dutch-speaking Brussels Free University (Vrije Universiteit Brussel), Brussels</wicri:regionArea><placeName><settlement type="city">Bruxelles</settlement><region nuts="2">Région de Bruxelles-Capitale</region></placeName></affiliation></author><author><name sortKey="Goossens, A" sort="Goossens, A" uniqKey="Goossens A" first="A." last="Goossens">A. Goossens</name><affiliation wicri:level="3"><country xml:lang="fr">Belgique</country><wicri:regionArea>Centre For Reproductive Medicine, University Hospital, Dutch-speaking Brussels Free University (Vrije Universiteit Brussel), Brussels</wicri:regionArea><placeName><settlement type="city">Bruxelles</settlement><region nuts="2">Région de Bruxelles-Capitale</region></placeName></affiliation></author><author><name sortKey="Van Steirteghem, A" sort="Van Steirteghem, A" uniqKey="Van Steirteghem A" first="A." last="Van Steirteghem">A. Van Steirteghem</name><affiliation wicri:level="3"><country xml:lang="fr">Belgique</country><wicri:regionArea>Centre For Reproductive Medicine, University Hospital, Dutch-speaking Brussels Free University (Vrije Universiteit Brussel), Brussels</wicri:regionArea><placeName><settlement type="city">Bruxelles</settlement><region nuts="2">Région de Bruxelles-Capitale</region></placeName></affiliation></author><author><name sortKey="Devroey, P" sort="Devroey, P" uniqKey="Devroey P" first="P." last="Devroey">P. Devroey</name><affiliation wicri:level="3"><country xml:lang="fr">Belgique</country><wicri:regionArea>Centre For Reproductive Medicine, University Hospital, Dutch-speaking Brussels Free University (Vrije Universiteit Brussel), Brussels</wicri:regionArea><placeName><settlement type="city">Bruxelles</settlement><region nuts="2">Région de Bruxelles-Capitale</region></placeName></affiliation></author><author><name sortKey="Tournaye, H" sort="Tournaye, H" uniqKey="Tournaye H" first="H." last="Tournaye">H. Tournaye</name><affiliation wicri:level="3"><country xml:lang="fr">Belgique</country><wicri:regionArea>Centre For Reproductive Medicine, University Hospital, Dutch-speaking Brussels Free University (Vrije Universiteit Brussel), Brussels</wicri:regionArea><placeName><settlement type="city">Bruxelles</settlement><region nuts="2">Région de Bruxelles-Capitale</region></placeName></affiliation></author></analytic><monogr></monogr><series><title level="j">Human Reproduction</title><title level="j" type="abbrev">Hum. Reprod.</title><idno type="ISSN">0268-1161</idno><idno type="eISSN">1460-2350</idno><imprint><publisher>Oxford University Press</publisher><date type="published" when="2006-06">2006-06</date><biblScope unit="volume">21</biblScope><biblScope unit="issue">6</biblScope><biblScope unit="page" from="1551">1551</biblScope><biblScope unit="page" to="1554">1554</biblScope></imprint><idno type="ISSN">0268-1161</idno></series><idno type="istex">96E1A1B9B1A984EA714030DA2F69002757219123</idno><idno type="DOI">10.1093/humrep/del012</idno><idno type="local">012</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0268-1161</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>TESE</term><term>azoospermia</term><term>repeated TESE</term><term>testicular sperm</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">BACKGROUND: Little is known about the extraction rate in repeated sperm retrieval procedures in azoospermic patients. This study aimed to assess the feasibility of repeated sperm recovery in these patients. METHODS: A total of 1066 azoospermic men had their first sperm recovery between 1 January 1995 and 31 December 2003. A total of 381 men had obstructive azoospermia (OA), 628 nonobstructive azoospermia (NOA) and 57 showed hypospermatogenesis. RESULTS: Overall, sperm could be retrieved in all procedures in the 598 cycles performed in OA men (100%). A total of 117, 57, 24, 11, 7 and 1 men underwent, respectively, two, three, four, five, six and seven sperm retrievals; all were successful. Of the 784 procedures performed on the 628 men with NOA, sperm could be retrieved in 384 procedures (49%). During the first testicular sperm extraction (TESE) procedure, sperm could be extracted in 261 men with NOA (41.6%). A total of 103 men had a second attempt, 34 had a third attempt, 11 had a fourth attempt, 6 had a fifth attempt and 2 had a sixth attempt. In these cycles, sperm could be extracted in, respectively, 77 (74.7%), 28 (82.3%), 11 (100%), 5 (83.3%) and 2 (100%) men. CONCLUSION: Repeated TESE ensures a high sperm recovery rate even in patients with NOA. In NOA patients, studies reporting on TESE may therefore overestimate the retrieval rate by reallocating successful patients. These data also show that when no spermatozoa can be obtained after thawing cryopreserved testicular sperm for ICSI in NOA patients, a repeat TESE procedure can be planned.</div></front></TEI><affiliations><list><country><li>Belgique</li><li>Espagne</li></country><region><li>Catalogne</li><li>Région de Bruxelles-Capitale</li></region><settlement><li>Bruxelles</li></settlement></list><tree><country name="Belgique"><region name="Région de Bruxelles-Capitale"><name sortKey="Vernaeve, Vale Rie" sort="Vernaeve, Vale Rie" uniqKey="Vernaeve V" first="Vale Rie" last="Vernaeve">Vale Rie Vernaeve</name></region><name sortKey="Devroey, P" sort="Devroey, P" uniqKey="Devroey P" first="P." last="Devroey">P. Devroey</name><name sortKey="Goossens, A" sort="Goossens, A" uniqKey="Goossens A" first="A." last="Goossens">A. Goossens</name><name sortKey="Tournaye, H" sort="Tournaye, H" uniqKey="Tournaye H" first="H." last="Tournaye">H. Tournaye</name><name sortKey="Van Steirteghem, A" sort="Van Steirteghem, A" uniqKey="Van Steirteghem A" first="A." last="Van Steirteghem">A. Van Steirteghem</name><name sortKey="Verheyen, G" sort="Verheyen, G" uniqKey="Verheyen G" first="G." last="Verheyen">G. Verheyen</name></country><country name="Espagne"><region name="Catalogne"><name sortKey="Vernaeve, Vale Rie" sort="Vernaeve, Vale Rie" uniqKey="Vernaeve V" first="Vale Rie" last="Vernaeve">Vale Rie Vernaeve</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Belgique/explor/OpenAccessBelV2/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 001648 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 001648 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Belgique
|area= OpenAccessBelV2
|flux= Main
|étape= Exploration
|type= RBID
|clé= ISTEX:96E1A1B9B1A984EA714030DA2F69002757219123
|texte= How successful is repeat testicular sperm extraction in patients with azoospermia?
}}
| This area was generated with Dilib version V0.6.25. |  |